Antiaging Labs Field Notes

Rethinking mitochondrial aging: what 750,000 genomes tell us about longevity

Fri, 06 Jun 2026 09:00:00 +0530

For decades, mitochondrial aging was explained as oxidative rust. A new Nature study of 736,000 people says blood mtDNA mutations look like replication copy-errors amplified by clonal hematopoiesis in bone marrow, not daily wear-and-tear.

What changed: mutations spike around age 60 because hidden stem-cell clones expand, not because cells suddenly start rusting. That reframes antioxidants, mitophagy, and what to track next.

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The four levers that actually move your biomarkers in 90 days

Tue, 02 Jun 2026 09:00:00 +0530

Almost everything you can change runs through four levers: nutrition, training, sleep, and a short list of supplements.

We rank what the evidence actually supports, and how much each lever moves the needle in a 90-day measured loop.

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Biological age, honestly: what PhenoAge can and can't tell you

Sat, 30 May 2026 09:00:00 +0530

Biological-age scores are real science and routinely oversold.

What PhenoAge measures, what an epigenetic clock is, and how to read your number without fooling yourself.

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Your blood report uses the wrong reference ranges

Thu, 28 May 2026 09:00:00 +0530

Normal on a lab report is the average of everyone who walked into a lab, the unwell included. Optimal is a different number.

Why your report can say fine when you're not, and what to look at instead.

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